Structure of PDB 6nc6 Chain B Binding Site BS01

Receptor Information
>6nc6 Chain B (length=461) Species: 484019 (Thermosipho africanus TCF52B) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SILFSIATFFSRILGLFRDVLFAKYFGVSYELDAYFIAIMFPFFLRKVFG
EGAMSSAFVPLYSEKSGEEKDKFLSSVINGFSLIILALVILSYFFPELII
NLFGAGSSHETKILAKKLLLITSPSIYFIFLWAISYSILNTNNKFFWPAL
TPSISNITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIKHKYYF
TIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSFYDKGSISYLQYASRF
YLLPYGLFAVSVSTVVLSKISNDRKNFNYHLNDALKTTLFFTIPSMVGLI
FLSTPIIRFFYEHGAFTSKDTLITSKILIAYTLGLPFYGIYSTISRSYHA
IKNTKTPFIAATIVSLSNIILDIIFGLKYGPIGVALATSIAGIIGVLYLL
FSVKTFPIKDFLKISLNSLIMLFVIYLTDFTDNEFWFLIQILIGILVYLI
FSSIFYRDLIR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6nc6 Chain B Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6nc6 Visualizing conformation transitions of the Lipid II flippase MurJ.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		H210 H213
Binding residue
(residue number reindexed from 1)		H204 H207
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015648 lipid-linked peptidoglycan transporter activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0015836 lipid-linked peptidoglycan transport
GO:0034204 lipid translocation
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6nc6, PDBe:6nc6, PDBj:6nc6
PDBsum6nc6
PubMed30988294
UniProtB7IE18|MURJ_THEAB Lipid II flippase MurJ (Gene Name=murJ)

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