Structure of PDB 6n6i Chain B Binding Site BS01

Receptor Information
>6n6i Chain B (length=186) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLII
KQPDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTP
PGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEE
YEFAPKKAASHRALDDISESIKELQFYRNNIFKKKI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6n6i A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation.
Resolution1.431 Å
Binding residue
(original residue number in PDB)		Y132 R133
Binding residue
(residue number reindexed from 1)		Y131 R132
Enzymatic activity
Enzyme Commision number 3.1.15.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6n6i, PDBe:6n6i, PDBj:6n6i
PDBsum6n6i
PubMed31225796
UniProtQ9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial (Gene Name=REXO2)

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