Structure of PDB 6l85 Chain B Binding Site BS01

Receptor Information

>6l85 Chain B (length=401) Species: 243274 (Thermotoga maritima MSB8)

MTILIIAGILGFIMAFSIGANDVANSMATAVGARAITVRQAALIAMFLEF
LGAVMFGSHVSQTIVKGIVEVEKVQPVELMYGALSALIAASFWILIATNW
GYPVSTTHSIVGGMMGFGLVAVGINGVNWKTFLFIVLSWVVSPVLGGLIS
FVMFKLISLSVFHTKNPKKSSTVAIPFFISLAIFTMISLFVKKTLKQPLS
ESFLLGIAFSLVTFFVVHFAVRKLINEKKDVYDAVENVFKRAQILTSCYV
SFSHGANDVANAAGPVAAVMIVASTGVVPKTVEIPFLALLLGGIGISLGV
FFLGQKVMETVGEKITTLTNSRGFTVDFSTATTVLLASSLGLPISTTHVV
VGAVTGVGFARGLEMVNVGVLKNIVISWLLIVPTVAATSAAVYWVLKLIL
K

Ligand information

• Ligand ID: PO4
• InChI: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
• InChIKey: NBIIXXVUZAFLBC-UHFFFAOYSA-K
• SMILES:
  CACTVS 3.341: [O-][P]([O-])([O-])=O
  ACDLabs 10.04: [O-]P([O-])([O-])=O
  OpenEye OEToolkits 1.5.0: [O-]P(=O)([O-])[O-]
• Formula: O4 P
• Name: PHOSPHATE ION
• DrugBank: DB14523
• PDB chain: 6l85 Chain B Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6l85 Structure of the sodium-dependent phosphate transporter reveals insights into human solute carrier SLC20.
• Resolution: 2.302 Å
• Binding residue (original residue number in PDB): D22 S105 T106 T107 D258 S345 T346 T347
• Binding residue (residue number reindexed from 1): D22 S105 T106 T107 D258 S345 T346 T347
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005315 phosphate transmembrane transporter activity

Biological Process

• GO:0006817 phosphate ion transport
• GO:0015698 inorganic anion transport
• GO:0035435 phosphate ion transmembrane transport

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:6l85, PDBe:6l85, PDBj:6l85
• PDBsum: 6l85
• PubMed: 32821837
• UniProt: Q9WY99