Structure of PDB 6l1o Chain B Binding Site BS01

Receptor Information
>6l1o Chain B (length=392) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHI
VEALREASLNPSFHGYGPFRGYPFLKEAIAAFYKREYGVTINPETEVALF
GGGKAGLYVLTQCLLNPGDIALVPNPGYPEYLSGITMARAELYEMPLYEE
NGYLPDFEKIDPAVLEKAKLMFLNYPNNPTGAVADAAFYAKAAAFAKEHN
IHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAELYSFSKTFNMAGWRMAF
AVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDPEHTESLKRIYKE
RIDFFTALCEKELGWKMEKPKGTFYVWAEIPNTFETSHQFSDYLLEHAHV
VVTPGEIFGSNGKRHVRISMVSKQEDLREFVTRIQKLNLPFG
Ligand information
Ligand IDTYR
InChIInChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChIKeyOUYCCCASQSFEME-QMMMGPOBSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(N)Cc1ccc(O)cc1
OpenEye OEToolkits 1.5.0c1cc(ccc1C[C@@H](C(=O)O)N)O
OpenEye OEToolkits 1.5.0c1cc(ccc1CC(C(=O)O)N)O
CACTVS 3.341N[CH](Cc1ccc(O)cc1)C(O)=O
CACTVS 3.341N[C@@H](Cc1ccc(O)cc1)C(O)=O
FormulaC9 H11 N O3
NameTYROSINE
ChEMBLCHEMBL925
DrugBankDB00135
ZINCZINC000000266964
PDB chain6l1o Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6l1o Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		F17 Q39 G40 K104 Y128 E130 Y325 R367
Binding residue
(residue number reindexed from 1)		F17 Q39 G40 K104 Y128 E130 Y325 R367
Annotation score4
Enzymatic activity
Enzyme Commision number 2.6.1.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process
GO:0017000 antibiotic biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6l1o, PDBe:6l1o, PDBj:6l1o
PDBsum6l1o
PubMed32134000
UniProtP39643|BACF_BACSU Transaminase BacF (Gene Name=bacF)

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