Structure of PDB 6kuj Chain B Binding Site BS01

Receptor Information
>6kuj Chain B (length=705) Species: 1173138 (Influenza D virus (D/swine/Oklahoma/1334/2011)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEINPYLLMLNNDITSMISLTYPYTGAPPMSHGTSTKYSMETVSRTYSYS
RTKKEVPSGIFPIERRKFCNTIEDKENLEKPNGNVDINFMLSLAEMLEEK
MGKGFFKFCANEAEAEILKMHFSKLTEGRQTYDWTSERNMPAATALQLTV
DAIQETQGTFKGTTMVEYCNKILEMMDWPEVKFKKVTLMITKIGREEFIK
RICTINTMAKDGERGKYKRRAIATPGMGIRPFSKIVETLAQKICERLAES
GLPVEKKAKLKTTVSSTNSKLQEGQFMVNITGDNSKWNECQQPEAYLAML
AYITKDSSNLMKDLCSVAPTLFCNKYVKMGQGFRAKNKRKTKEIVIPAKK
MKERKELMNAEWRDLFETIEPYMDGECCFLGGGMLMGMFNMLSTVFGVMT
LNYREERNCYWTGLQSSDDFVLFCISRTWPEMEMTILKFIAVCKLMGINM
SLEKSYGCLPELFEFTSMFFSGDFVSNIALELPAFTTAGMNEGTDFTAAM
SVIRTNMINNGLSPGTALMALRICLQEFRATYRVHPYDSGVKNHRMKIIR
KFIETIENKDGLLISDGGKLMNNISSLHIPEEILKEDLMDPSYRNRVFNP
RNPFTQFAVVSTHSFRTRSNRTLLNTDMRAMALEEKRYQVVCNMYRSVFE
SADVNTPIGSMSMGEAIEAKILDRARTQFENGIIGGEEYSEIKRLIEDAK
RQRLS
Ligand information
Receptor-Ligand Complex Structure
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PDB6kuj Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation
Resolution3.4 Å
Binding residue
(original residue number in PDB)
A558 R561 H563 N571 H572
Binding residue
(residue number reindexed from 1)
A530 R533 H535 N543 H544
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:6kuj, PDBe:6kuj, PDBj:6kuj
PDBsum6kuj
PubMed31209309
UniProtK9LH03

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