Structure of PDB 6k1f Chain B Binding Site BS01

Receptor Information
>6k1f Chain B (length=587) Species: 575 (Raoultella planticola) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLPKIGIRPVIDGRRMGVRESLEAQTMNMAKATAALISEKLRHACGAQIE
CVIADTCIAGMAESAACEEKFSRQNVGVTITVTPCWCYGSETIDMDPLRP
KAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTTIPAD
VEEKLLRFARAGLAVASMKGKSYLSVGGVSMGIAGSIVDHNFFESWLGMK
VQAVDMTELRRRIDQKIYDEVELEMALAWADKNFRYGEDQNAQHYKRDEE
QSRAVLKESLLMAMCIRDMMQGNEKLAEKGLVEESLGYNAIAAGFQGQRH
WTDQYPNGDTAEALLNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTG
TAQVFADVRTYWSPDAVERVTGQPLTGLAEHGIIHLINSGSAALDGSCQQ
RDEEGKPTMKPHWEISQKEADACLAATEWCPAIHEYFRGGGYSSRFLTEG
GVPFTMTRVNLIKGLGPVLQIAEGWSVELPKAMHDQLDARTNSTWPTTWF
APRLTGKGPFADVYSVMANWGANHGVLTIGHVGADFITLAAMLRIPVCMH
NVEEGKIYRPSSWAAHGMDTEGQDYRACQNYGPLYKR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6k1f Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6k1f Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase fromRaoultellasp. and the biochemical and structural analyses of the enzyme.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		E337 D361 H528
Binding residue
(residue number reindexed from 1)		E333 D357 H524
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E337 D361 H528
Catalytic site (residue number reindexed from 1) E333 D357 H524
Enzyme Commision number 5.3.1.25: L-fucose isomerase.
Gene Ontology
Molecular Function
GO:0008736 L-fucose isomerase activity
GO:0008790 arabinose isomerase activity
GO:0016853 isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0005996 monosaccharide metabolic process
GO:0006004 fucose metabolic process
GO:0019317 fucose catabolic process
GO:0019571 D-arabinose catabolic process
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6k1f, PDBe:6k1f, PDBj:6k1f
PDBsum6k1f
PubMed31827610
UniProtA0A443VNT1

[Back to BioLiP]