Structure of PDB 6jim Chain B Binding Site BS01

Receptor Information
>6jim Chain B (length=455) Species: 37124 (Chikungunya virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIIETPRGAIKVTAQPTDHVVGEYLVLSPQTVLRSQKLSLIHALAEQVKT
CTHNAYDGRVLVPSGYAISPEDFQSLSESATMVYNEREFVNRKLHHIAMH
GPALNTDEESYELVRAERTEHEYVYDVDQRRCCKKEEAAGLVLVGDLTNP
PYHEFAYEGLKIRPACPYKIAVIGVFGVPGSGKSAIIKNLVTRQDLVTSG
KKENCQEITTDVMRQRGLEISARTVDSLLLNGCNRPVDVLYVDEAFACHS
GTLLALIALVRPRQKVVLCGDPKQCGFFNMMQMKVNYNHNICTQVYHKSI
SRRCTLPVTAIVSSLHYEGKMRTTNEYNKPIVVDTTGSTKPDPGDLVLTC
FRGWVKQLQIDYRGYEVMTAAASQGLTRKGVYAVRQKVNENPLYASTSEH
VNVLLTRTEGKLVWKTLSGDPWIKTLQNPPKGNFKATIKEWEVEHASIMA
GICSH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jim Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E95 Y161 F164 K210 K211 T233 D235 S236 L239 N240 F287 F360 R361 G362 W363 T378 A380 N400 L402 H409
Binding residue
(residue number reindexed from 1)		E86 Y152 F155 K201 K202 T224 D226 S227 L230 N231 F278 F351 R352 G353 W354 T369 A371 N391 L393 H400
Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6jim, PDBe:6jim, PDBj:6jim
PDBsum6jim
PubMed31000599
UniProtA0A076V769

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