Structure of PDB 6iwd Chain B Binding Site BS01

Receptor Information
>6iwd Chain B (length=49) Species: 333761 (human papillomavirus 18) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPQRHTMLCMCCKCEARIELVVESSADDLRAFQQLFLNTLSFVCPWCAS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6iwd Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6iwd Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C65 C68 C98 C101
Binding residue
(residue number reindexed from 1)		C11 C14 C44 C47
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6iwd, PDBe:6iwd, PDBj:6iwd
PDBsum6iwd
PubMed31323018
UniProtP06788|VE7_HPV18 Protein E7 (Gene Name=E7)

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