Structure of PDB 6hbs Chain B Binding Site BS01

Receptor Information
>6hbs Chain B (length=413) Species: 33050 (Sphingopyxis macrogoltabida) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTRQKDLRERAERVIPGGMYGHESTRLLPPEFPQFFRRALGARIWDADEQ
PYIDYMCAYGPNLLGYRQSEIEAAADAQRLLGDTMTGPSEIMVNLAEAFV
GMVRHADWAMFCKNGSDATSTAMVLARAHTGRKTILCAKGAYHGASPWNT
PHTAGILASDRVHVAYYTYNDAQSLSDAFKAHDGDIAAVFATPFRHEVFE
DQALAQLEFARTARKCCDETGALLVVDDVRAGFRVARDCSWTHLGIEPDL
SCWGKCFANGYPISALLGSNKARDAARDIFVTGSFWFSAVPMAAAIETLR
IIRETPYLETLIASGAALRAGLEAQSQRHGLELKQTGPAQMPQIFFADDP
DFRIGYAWAAACLKGGVYVHPYHNMFLSAAHTVDDVTETLEATDRAFSAV
LRDFASLQPHPIL
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain6hbs Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6hbs Structure of PLP internal aldimine form of Sphingopyxis sp. MTA144 FumI protein
Resolution1.65 Å
Binding residue
(original residue number in PDB)		G286 S287
Binding residue
(residue number reindexed from 1)		G283 S284
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Y145 D230 K258
Catalytic site (residue number reindexed from 1) Y142 D227 K255
Enzyme Commision number 2.6.1.-
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:6hbs, PDBe:6hbs, PDBj:6hbs
PDBsum6hbs
PubMed
UniProtD2D3B2|FUMI_SPHMC Aminopentol aminotransferase (Gene Name=fumI)

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