Structure of PDB 6h3r Chain B Binding Site BS01

Receptor Information
>6h3r Chain B (length=121) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSPVVKRLLGWKKSNGQEEKWSEKAVKSLVKKLKKTGRLDELEKAITTQN
MNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC
EYAFNLKKDEVCVNPYHYQRV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6h3r Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6h3r Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-beta signaling
Resolution2.75 Å
Binding residue
(original residue number in PDB)		C74 C149 C161 H166
Binding residue
(residue number reindexed from 1)		C55 C100 C112 H117
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6h3r, PDBe:6h3r, PDBj:6h3r
PDBsum6h3r
PubMed
UniProtB7Z5N5

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