Structure of PDB 6gen Chain B Binding Site BS01

Receptor Information
>6gen Chain B (length=97) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKEIKLARRLRGE
Ligand information
>6gen Chain I (length=173) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcattaatgcatccgcggccgccctggagaatcccggtgccgaggccgct
caattggtcgtagacagctctagcaccgcttaaacgcacgtacgcgctgt
cccccgcgttttaaccgccaaggggattactccctagtctccaggcacgt
gtcagatatatacatcctgtgca
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6gen Structure and dynamics of the yeast SWR1-nucleosome complex.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
R40 V46 R49
Binding residue
(residue number reindexed from 1)
R4 V10 R13
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008823 cupric reductase (NADH) activity
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006355 regulation of DNA-templated transcription
GO:0006878 intracellular copper ion homeostasis
GO:0009060 aerobic respiration
GO:0009303 rRNA transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0043935 sexual sporulation resulting in formation of a cellular spore
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:0070911 global genome nucleotide-excision repair
Cellular Component
GO:0000500 RNA polymerase I upstream activating factor complex
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex
GO:0043505 CENP-A containing nucleosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6gen, PDBe:6gen, PDBj:6gen
PDBsum6gen
PubMed30309918
UniProtP61830|H3_YEAST Histone H3 (Gene Name=HHT1)

[Back to BioLiP]