Structure of PDB 6g85 Chain B Binding Site BS01

Receptor Information
>6g85 Chain B (length=359) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDNTIEFLRGRVYLGAYDYTPEDTDELVFFTVEDAIFYNSFHLDFGPMNI
GHLYRFAVIFHEILNDPENANKAVVFYSSASTRQRANAACMLCCYMILVQ
AWTPHQVLQPLAQVDPPFMPFRDAGYSNADFEITIQDVVYGVWRAKEKGL
IDLHSFNLESYEKYEHVEFGDFNVLTPDFIAFASPQEDHPKHLNQPFKSV
LNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKN
FVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLR
FIRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAIGGLYPLISLEE
YRLQKKKLK
Ligand information
>6g85 Chain D (length=15) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AFTDVPALNYPATPP
Receptor-Ligand Complex Structure
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PDB6g85 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase.
Resolution1.528 Å
Binding residue
(original residue number in PDB)		Y60 H67 V105 Q106 W108 Q112 L159
Binding residue
(residue number reindexed from 1)		Y54 H61 V99 Q100 W102 Q106 L153
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:6g85, PDBe:6g85, PDBj:6g85
PDBsum6g85
PubMed30455435
UniProtQ00684|CDC14_YEAST Tyrosine-protein phosphatase CDC14 (Gene Name=CDC14)

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