Structure of PDB 6g84 Chain B Binding Site BS01

Receptor Information
>6g84 Chain B (length=368) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVYLDNTIEFLRGRVYLGAYDYTPEDTDELVFFTVEDAIFYNSFHLDFGP
MNIGHLYRFAVIFHEILNDPENANKAVVFYSSASTRQRANAACMLCCYMI
LVQAWTPHQVLQPLAQVDPPFMPFRDAGYSNADFEITIQDVVYGVWRAKE
KGLIDLHSFNLESYEKYEHVEFGDFNVLTPDFIAFASPQEDHPKGYLATK
SSHLNQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFED
GTCPDLSIVKNFVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYG
FTANECIGFLRFIRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAI
GGLYPLISLEEYRLQKKK
Ligand information
>6g84 Chain C (length=11) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AFTDVPALNYP
Receptor-Ligand Complex Structure
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PDB6g84 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		L14 Y60 L70 Q106 W108 Q112 H160
Binding residue
(residue number reindexed from 1)		L11 Y57 L67 Q103 W105 Q109 H157
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:6g84, PDBe:6g84, PDBj:6g84
PDBsum6g84
PubMed30455435
UniProtQ00684|CDC14_YEAST Tyrosine-protein phosphatase CDC14 (Gene Name=CDC14)

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