Structure of PDB 6g4w Chain B Binding Site BS01

Receptor Information
>6g4w Chain B (length=213) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVS
LADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTM
IEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMME
IMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKK
PKFELGKLMELHG
Ligand information
>6g4w Chain 2 (length=1563) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacg
ccggcggcgacgacccauucgaacgucugcccuaucaacuuucgauggua
gucgccgugccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaa
caauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaa
uccuuuaacgaggauccauuggagggcaagucuggcagcuccaauagcgu
auauuaaaguugcugcaguuaaaaagcucguaguuggaucucucucggcc
gaagcguuuacuuugaaaaaauuagaguguucaaagcaggccgccuggau
accgcagcuaggaauaauggaauaggaccgcgguucuauuuuguugguuu
ucggaacugaggccaugauuaagagggacggccgggggcauucguauugc
gccgcuagaggugaaauucuuggaccggcgcaagacggaccagagcgaaa
gcauuugccaagaauguuuucauuaaucaagaacgaaagucggagguucg
aagacgauaccgucguaguuccgaccauaaacgaugccgaccggcgaugc
ggcggcguuauucccaugacccgccgggcagcuuccgggaaaccaaaguc
uuuggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauug
acggaagggcaccaccaggaguggagccugcggcuuaauuugacucaaca
cgggaaaccucacccggcccggacacggacaggauugacagauugauagc
ucuuucucgauuccguggguggugcauggccguuccugguuaauuccgau
gacucuggcaugcuauucuuagagggacaaguggcguucagccacccgag
auugagcuaacaggucugugugcccuguccggggcugcacgcgcgcuaca
cugacuggcucagcguguccuacgccggcaggcgcggguaacccguugaa
ccccauucgugauggggaucggggauugcaauuauuccccaugaacgagg
aauucccaguaagugcgggucauaagcuugcguugauuaagucccugccc
uuugcaccgcgucgcuacuaccgauuggaugguuuagugaggcccucgga
ucggccccgccggggugcccuggcggagcgcugagaagacggucgaacuu
gacuaucuagaggaaguaaaagucggguuuccguaggugaaccugcggaa
ggaucauuaacgg
...<<<<<.[.(((.>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<......<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<<....>>>>>>..
.>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<
<..>>>>>>>.>>.>>>...>>....>>>.<<<....<<<....<<<<<<
<.........>>>>>>>>>>......>>>...<<<<<<<<....>>>>..
.>>>>.>>.<<.<<<..........>>>.>>.<.<<<..>>>.>...>>>
>>>.........<<<....<<<<...>>>>..>>>..>...>>.>.....
<<<<<<.<<.<<<....>>>.>>..>>>.>>>......<<..<.......
....>..>>.........<<<<<........<<<.>>>.>>>>>..>>>>
>>.>>>.........<.........<.<<...<<<.<<...<<.<<<<>>
>>>>...<<<<<<.<.......<<...<.......>.<<<<.>>>>...>
>......>.>>>..>>>........<.<<.<<<<<<<.............
..>>>>>>>.>>.>....>>....<<<<<<..<...<<<<..<<<.<<<<
<<<<...<<<......>>>......>>>>>>>>.>>>.......<<....
>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<....>>>>...>>>>>>>>..........<<<.<<.<<<..<.<
<<<<<.<<<........>>>>>>>>>.>..>>>...<<....>>...>>.
....>>>...>.<<<......<<<<....>>>>....>>>...))).]..
.<<.<<<<<<<..<<..<<<<<.<<<<.<<<<<<.......<........
>...........<<<<<......<<<<<<.......<..<<<........
>>>..>.....>>>>>>...<<<<<<<<<<<<<...<<<......>>>..
..<<<...<...<<......>>..>.....<<<<<.....>>>>>.....
...>>>...>>.>>>>.>>>>>>>....>>>>>...>>.>>>>.>>>.>.
..<<.<<<........<.<<<.<<<<....>>>>.>>>....>.......
..>>>.>>......<.....<<<<<..........>>>>>.....>....
.>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>
>>>>.<<<.<<....<<<<.<<....<<<<<<<<.<<<..<<<<.<<...
<<<<<<<<<<<<<<<<>>>>>>>>>>.>.>>>>>...>>.>>>>..>>>.
>>>>>>>>...>>.>>>>.....>>>>><<<<<<<<<....>>>>>>>>>
.............
Receptor-Ligand Complex Structure
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PDB6g4w Visualizing late states of human 40S ribosomal subunit maturation.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		M120 N148 Q149 R151 Q202 S203 I204 Y205
Binding residue
(residue number reindexed from 1)		M100 N128 Q129 R131 Q182 S183 I184 Y185
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0048027 mRNA 5'-UTR binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006413 translational initiation
GO:0030154 cell differentiation
GO:0042274 ribosomal small subunit biogenesis
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6g4w, PDBe:6g4w, PDBj:6g4w
PDBsum6g4w
PubMed29875412
UniProtP61247|RS3A_HUMAN Small ribosomal subunit protein eS1 (Gene Name=RPS3A)

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