Structure of PDB 6g2k Chain B Binding Site BS01

Receptor Information
>6g2k Chain B (length=81) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVT
MTNYEEAAMAIASLNGYRLGDKILQVSFKTN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6g2k HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Resolution2.01 Å
Binding residue
(original residue number in PDB)		C245 F247 Y249 I276 F279 F289 Q316 K320 T321
Binding residue
(residue number reindexed from 1)		C4 F6 Y8 I35 F38 F48 Q75 K79 T80
Binding affinityPDBbind-CN: Kd=19.3uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6g2k, PDBe:6g2k, PDBj:6g2k
PDBsum6g2k
PubMed30418581
UniProtQ15717|ELAV1_HUMAN ELAV-like protein 1 (Gene Name=ELAVL1)

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