Structure of PDB 6g0s Chain B Binding Site BS01

Receptor Information
>6g0s Chain B (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPTE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6g0s Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution1.48 Å
Binding residue
(original residue number in PDB)
W81 K91 L92 D96 N140 M149
Binding residue
(residue number reindexed from 1)
W39 K49 L50 D54 N98 M107
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6g0s, PDBe:6g0s, PDBj:6g0s
PDBsum6g0s
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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