Structure of PDB 6fuw Chain B Binding Site BS01

Receptor Information
>6fuw Chain B (length=370) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYN
DLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASS
GEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQS
NMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL
RGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNT
VMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWH
PVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHIL
CSGSNDHTSKFWTRNRPGDK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6fuw Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
Resolution3.07 Å
Binding residue
(original residue number in PDB)
F43 D44 G45 R47 M48 R49 V52 K117 F153 I156
Binding residue
(residue number reindexed from 1)
F3 D4 G5 R7 M8 R9 V12 K77 F113 I116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0031124 mRNA 3'-end processing

View graph for
Biological Process
External links
PDB RCSB:6fuw, PDBe:6fuw, PDBj:6fuw
PDBsum6fuw
PubMed29358758
UniProtQ9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 (Gene Name=WDR33)

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