Structure of PDB 6fpy Chain B Binding Site BS01

Receptor Information

>6fpy Chain B (length=599) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKT
AFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTME
QFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDV
DIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSC
PTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVV
FVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSL
VQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNH
ASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFL
EVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLA
LTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDE
EEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQAL
QMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDRRTFVLSALQPSP

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6fpy Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6fpy Heavy chain-1 of inter-alpha-inhibitor has an integrin-like structure with immune regulatory activities
Resolution	2.339 Å
Binding residue (original residue number in PDB)	S300 S302 D403
Binding residue (residue number reindexed from 1)	S256 S258 D359
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:6fpy, PDBe:6fpy, PDBj:6fpy
PDBsum	6fpy
PubMed	32144206
UniProt	P19827\|ITIH1_HUMAN Inter-alpha-trypsin inhibitor heavy chain H1 (Gene Name=ITIH1)

[Back to BioLiP]