Structure of PDB 6fo2 Chain B Binding Site BS01

Receptor Information
>6fo2 Chain B (length=409) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLAS
SLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFL
LNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNALA
NSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAEQF
LNIRGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVLQHVL
GAGPHVKRGSNATSSLYQAVAKGVHEPFDVSAFNASYSDSGLFGFYTISQ
AASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFL
DEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGN
LGHTPFIDE
Ligand information
Receptor-Ligand Complex Structure
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PDB6fo2 X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		E90 L96 S97 V98 T99 T101 F312
Binding residue
(residue number reindexed from 1)		E67 L73 S74 V75 T76 T78 F283
Enzymatic activity
Catalytic site (original residue number in PDB) H67 R70 L71 L140 D147
Catalytic site (residue number reindexed from 1) H44 R47 L48 L117 D124
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fo2, PDBe:6fo2, PDBj:6fo2
PDBsum6fo2
PubMed29765610
UniProtP23004|QCR2_BOVIN Cytochrome b-c1 complex subunit 2, mitochondrial (Gene Name=UQCRC2)

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