Structure of PDB 6fo0 Chain B Binding Site BS01

Receptor Information
>6fo0 Chain B (length=414) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRL
ASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILME
FLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNA
LANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAE
QFLNIRLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVL
QHVLGAGPHVKRGSNATSSLYQAVAKGVHEPFDVSAFNASYSDSGLFGFY
TISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESS
EGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMA
ASGNLGHTPFIDEL
Ligand information
Receptor-Ligand Complex Structure
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PDB6fo0 X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		R70 K95 L96 V98 T99 S100 T101 Q276 F312
Binding residue
(residue number reindexed from 1)		R49 K74 L75 V77 T78 S79 T80 Q251 F287
Enzymatic activity
Catalytic site (original residue number in PDB) H67 R70 L71 L140 D147
Catalytic site (residue number reindexed from 1) H46 R49 L50 L119 D126
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fo0, PDBe:6fo0, PDBj:6fo0
PDBsum6fo0
PubMed29765610
UniProtP23004|QCR2_BOVIN Cytochrome b-c1 complex subunit 2, mitochondrial (Gene Name=UQCRC2)

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