Structure of PDB 6fmq Chain B Binding Site BS01
Receptor Information
>6fmq Chain B (length=285) Species:
9606
(Homo sapiens) [
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GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLL
YAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYA
VGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGG
YDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDG
HTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
>6fmq Chain D (length=5) Species:
32630
(synthetic construct) [
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ETGEL
Receptor-Ligand Complex Structure
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PDB
6fmq
Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y334 S363 N382 R415 R483 S508 Y525 Q530 S555 Y572 F577 S602
Binding residue
(residue number reindexed from 1)
Y10 S39 N58 R91 R159 S184 Y201 Q206 S231 Y248 F253 S278
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6fmq
,
PDBe:6fmq
,
PDBj:6fmq
PDBsum
6fmq
PubMed
29927029
UniProt
Q14145
|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)
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