Structure of PDB 6fgx Chain B Binding Site BS01

Receptor Information
>6fgx Chain B (length=193) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEM
RSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQE
DVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGM
DMWASLEHKIRAETEKYRDLLKECATEITEVEDKLQQIHSEIT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6fgx Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6fgx Structural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D107 E174
Binding residue
(residue number reindexed from 1)		D75 E142
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.6.5: GTP diphosphokinase.
Gene Ontology
Molecular Function
GO:0008728 GTP diphosphokinase activity
GO:0016301 kinase activity
Biological Process
GO:0015969 guanosine tetraphosphate metabolic process
GO:0015970 guanosine tetraphosphate biosynthetic process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6fgx, PDBe:6fgx, PDBj:6fgx
PDBsum6fgx
PubMed29391580
UniProtW8U368

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