Structure of PDB 6fbr Chain B Binding Site BS01

Receptor Information
>6fbr Chain B (length=81) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRCLI
DKRQRNRCQYCRYQKCLAMGMKREAVQEERQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6fbr Modulation of RXR-DNA complex assembly by DNA context.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		S127 H128 M129 K145 H146 Y147 K156 R164 Q206 E208 R209
Binding residue
(residue number reindexed from 1)		S2 H3 M4 K20 H21 Y22 K31 R39 Q77 E79 R80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6fbr, PDBe:6fbr, PDBj:6fbr
PDBsum6fbr
PubMed30476562
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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