Structure of PDB 6f3h Chain B Binding Site BS01

Receptor Information
>6f3h Chain B (length=790) Species: 5478 (Nakaseomyces glabratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRGNMEQYQKAQKLSFDPAELLRTSLNVGDIVLLKQCTSELTMCVNLPQS
TTDPRYTFAKKDGTLVYAMKNSVILRIPKDLPEEVNQLLKRESNLPVLTR
QLIVSFTLATFTKFAWTQLPIVLKKLELIHRYLQDSRGSKHVNFMSLVRI
IKNLNIKEATDAYVRKVIDESMSVVNKSIDPTTLLATYWGVREQQQNNLW
GSVYTNTALLSPTTVAVLPLKKAHLFYQEVITRLESNDYQEIKAFAKLVN
DKDYHSIAKRYDYIRTLLNDYAAGNIEENAVLTTIISKIFRHIDMYRDQD
VTRSLCGKLLVEISPQSNSSNFILGNWDLNIPKGISSVEQKLYDTAMPTI
VTDRYDFGDMPVFCIDSEDAHEINDGISIEELDGVRSRIHIHIADPAGLF
PESFDYTKSGISDDVLRVSLKRAFTTYLPDLVVPMLPKSFCNRADLGKHD
RKTETISFSFELVNKEDGGLHVDYDTFQVRLGIVSNFPKVTYDKVDSILN
GDDNSLPSKQKKQLELLHTLATKLLHKRIHDDNAVVFGDGFNKGLVSLSP
DCIPTFYDQSQTKSTLLVSEFMILTNKLCAAFFQENKIPGVYRCYNGLNL
GNQAKAQFELLKENIKLGKLPSLKDITKISSQLSSSFYSPFPLPHKMIGN
TAYLTVTSPMRRGPDLINHLQLHRFLKKLPLCFKQEYLDQYVWSFQARAD
ILKIFQRHSSTYWTLKHLEQSGTKTHDVIVTSVPQNGTVNCLFPEYSYAR
GTLKLDPAMKKIPRIGDTIRHCKVESIHPLDGILTLTHVN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6f3h Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Resolution2.703 Å
Binding residue
(original residue number in PDB)		T306 A473 H474 E475 N477 Y530 Y595 F640 F644 N645 S677 M680 I681 R701 S742 S743 S744 H753 M755 I756 Y761 T765 R769 R858
Binding residue
(residue number reindexed from 1)		T207 A370 H371 E372 N374 Y427 Y492 F537 F541 N542 S569 M572 I573 R593 S634 S635 S636 H645 M647 I648 Y653 T657 R661 R750
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
GO:0046872 metal ion binding
Biological Process
GO:0000957 mitochondrial RNA catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0045025 mitochondrial degradosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f3h, PDBe:6f3h, PDBj:6f3h
PDBsum6f3h
PubMed29311576
UniProtQ6FJE0

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