Structure of PDB 6f2a Chain B Binding Site BS01

Receptor Information

>6f2a Chain B (length=324) Species: 479433 (Catenulispora acidiphila DSM 44928) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VSAILVLTSSEASTLERVADLVTAHALYAAHDFCAQAQLAAAELPSRVVA
RLQEFAWGDMNEGHLLIKGLPQVRSLPPTPTSNVHAVAATTPMSRYQALI
NECVGRMIAYEAEGHGHTFQDMVPSAMSAHSQTSLGSAVELELHTEQAFS
PLRPDFVSLACLRGDPRALTYLFSARQLVATLTTQEIAMLREPMWTTTVD
ESFLAEGRTFLLGFERGPIPILSGADDDPFIVFDQDLMRGISAPAQELQQ
TVIRAYYAERVSHCLAPGEMLLIDNRRAVHGRSIFAPRFDGADRFLSRSF
IVADGSRSRHARSSFGRVVSARFS

Ligand information

InChI=1S/Fe/q+2

CWYNVVGOOAEACU-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Fe+2]
CACTVS 3.341	[Fe++]

Formula

Name

FE (II) ION

PDB chain

6f2a Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6f2a Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	H178 E180 H314
Binding residue (residue number reindexed from 1)	H144 E146 H280
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.14.11.-

Gene Ontology

	Molecular Function
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0016706	2-oxoglutarate-dependent dioxygenase activity
GO:0046872	metal ion binding
GO:0051213	dioxygenase activity

View graph for
Molecular Function

External links

PDB	RCSB:6f2a, PDBe:6f2a, PDBj:6f2a
PDBsum	6f2a
PubMed	30410048
UniProt	C7QJ42\|LYS3O_CATAD L-lysine 3-hydroxylase (Gene Name=Caci_0231)

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