Structure of PDB 6euo Chain B Binding Site BS01

Receptor Information
>6euo Chain B (length=335) Species: 1144313 (Flavobacterium sp. CF136) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEIPTSPLIIKITQQERNILSNVGNLLVKAFGNYENPDYIASLHLHAFQL
LPERITRILSQFGSDFSAEQYGAIVFQGLIEVDQDDLGPTPPNWQGADYG
KLNKYGFICSLLHGAVPSKPVQYYAQRKGGGLLHAVIPDEKMAATQTGSG
SKTDLFVHTEDAFLSNQADFLSFLYLRNEERVPSTLYSIRSHGKMNPVMK
KLFEPIYQCPKDSGPTASVLYGNRELPFIRFDAAEQIFNENAGQTSEALG
NLMDFWDEAKTLINSDYIPNSGDLIFVNNHLCAHGRSAFIAGQCERRQML
RMMSKTSLIHIRSVTRTDDPYFIMEEHLGKIFDLD
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain6euo Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6euo Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H176 E178 H312
Binding residue
(residue number reindexed from 1)		H158 E160 H284
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Molecular Function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6euo, PDBe:6euo, PDBj:6euo
PDBsum6euo
PubMed30410048
UniProtJ3BZS6|LYS4O_FLASC L-lysine 4-hydroxylase (Gene Name=PMI10_03368)

[Back to BioLiP]