Structure of PDB 6ec0 Chain B Binding Site BS01

Receptor Information
>6ec0 Chain B (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVAL
RQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDL
RN
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain6ec0 Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ec0 Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.
Resolution2.983 Å
Binding residue
(original residue number in PDB)		N212 D216
Binding residue
(residue number reindexed from 1)		N18 D22
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6ec0, PDBe:6ec0, PDBj:6ec0
PDBsum6ec0
PubMed31036554
UniProtP13645|K1C10_HUMAN Keratin, type I cytoskeletal 10 (Gene Name=KRT10)

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