Structure of PDB 6eb5 Chain B Binding Site BS01

Receptor Information
>6eb5 Chain B (length=229) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTFKHESYYATVNELTPVGTTIFTGFSGDNGATGPNGQIEYVIQYNPDDP
TSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRATTTTTLTVDV
LDGDDLGPMFLPCVLDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD
RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQK
FDLVIKAEQDNGHPLPAFAGLHIEILDEN
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6eb5 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6eb5 Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E137 E202 D236 G237 D239 D289
Binding residue
(residue number reindexed from 1)		E14 E75 D102 G103 D105 D150
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6eb5, PDBe:6eb5, PDBj:6eb5
PDBsum6eb5
PubMed32963095
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

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