Structure of PDB 6e20 Chain B Binding Site BS01

Receptor Information
>6e20 Chain B (length=133) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGVLIQNMSFKVGQTLTITGVPKPDSTNFAINIGHSPEDIALHMNPRFDA
HGDQCTIVCNSFQSGSWCEEHRDDNFPFIQDKEFQIKITFTNEEFLVTLP
DGSEIHFPNRQGSEKYKYMYFEGEVRIQGVEIK
Ligand information
Ligand IDGAL
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.2C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
OpenEye OEToolkits 1.7.2C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
FormulaC6 H12 O6
Namebeta-D-galactopyranose;
beta-D-galactose;
D-galactose;
galactose
ChEMBLCHEMBL300520
DrugBank
ZINCZINC000002597049
PDB chain6e20 Chain D Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6e20 Structure of the zebrafish galectin-1-L2 and model of its interaction with the infectious hematopoietic necrosis virus (IHNV) envelope glycoprotein.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H44 R48 N61 W68 E71
Binding residue
(residue number reindexed from 1)		H43 R47 N60 W67 E70
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016936 galactoside binding
GO:0030246 carbohydrate binding
GO:0043236 laminin binding
GO:0046872 metal ion binding
Biological Process
GO:0001944 vasculature development
GO:0002040 sprouting angiogenesis
GO:0048741 skeletal muscle fiber development
GO:0050769 positive regulation of neurogenesis
GO:0090303 positive regulation of wound healing
Cellular Component
GO:0005615 extracellular space

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6e20, PDBe:6e20, PDBj:6e20
PDBsum6e20
PubMed30834446
UniProtQ6TGN5

[Back to BioLiP]