Structure of PDB 6do4 Chain B Binding Site BS01
Receptor Information
>6do4 Chain B (length=318) Species:
9606
(Homo sapiens) [
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ACPAERSGHVAVSDGRHMFVWGGYKSFYLPREELWIYNMETGRWKKINTE
GDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRVLQWERIDCQ
GIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWHPRGW
NDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDAR
MNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDK
QPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFGGCANN
LLVHHRAAHSNEILIFSV
Ligand information
>6do4 Chain D (length=6) Species:
9606
(Homo sapiens) [
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GPSSGG
Receptor-Ligand Complex Structure
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PDB
6do4
Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
H109 K147 Y163 R189 W191 R236 R241 S269 W270 W321
Binding residue
(residue number reindexed from 1)
H75 K109 Y125 R148 W150 R195 R200 S228 W229 W280
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6do4
,
PDBe:6do4
,
PDBj:6do4
PDBsum
6do4
PubMed
30526872
UniProt
Q9Y2U9
|KLDC2_HUMAN Kelch domain-containing protein 2 (Gene Name=KLHDC2)
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