Structure of PDB 6dnh Chain B Binding Site BS01

Receptor Information
>6dnh Chain B (length=376) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYND
LVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSG
EFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSN
MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILR
GHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTV
MEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHP
VHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILC
SGSNDHTSKFWTRNRPGDKMRDRYNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6dnh Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
F43 D44 G45 R47 M48 R49 R112 N152 F153 I156
Binding residue
(residue number reindexed from 1)
F2 D3 G4 R6 M7 R8 R71 N111 F112 I115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0031124 mRNA 3'-end processing

View graph for
Biological Process
External links
PDB RCSB:6dnh, PDBe:6dnh, PDBj:6dnh
PDBsum6dnh
PubMed29208711
UniProtQ9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 (Gene Name=WDR33)

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