Structure of PDB 6dk7 Chain B Binding Site BS01

Receptor Information
>6dk7 Chain B (length=224) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEFLAKISHEIRTPMNGVLGMTELLLGTPLSAKQRDYVQTIHSAGNELLT
LINEILDISKLESGQIELDEVQFDLNALIEDCLDIFRVKAEQQRIELISF
TQPQVPRVIGGDPTRLRQVVLSLLDNAFKQTEEGEILLVVALDDQGETPR
LRIAVQDSGHPFDAKEREALLTAELHSGDFLSASKLGSHLGLIIARQLVR
LMGGEFGIQSSQGTTLSLTLPLDP
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain6dk7 Chain B Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6dk7 Helix Cracking Regulates the Critical Interaction between RetS and GacS in Pseudomonas aeruginosa.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E438 H457
Binding residue
(residue number reindexed from 1)		E23 H42
Annotation score3
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6dk7, PDBe:6dk7, PDBj:6dk7
PDBsum6dk7
PubMed30879888
UniProtQ9HUV7

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