Structure of PDB 6da1 Chain B Binding Site BS01

Receptor Information
>6da1 Chain B (length=138) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSC
QSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKN
IIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPD
Ligand information
>6da1 Chain C (length=16) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PSFDSFDFEDFPAALW
Receptor-Ligand Complex Structure
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PDB6da1 The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
Resolution2.00013 Å
Binding residue
(original residue number in PDB)		Q336 W338 M384 K388 R391 G392 Y395 Y396
Binding residue
(residue number reindexed from 1)		Q36 W38 M84 K88 R91 G92 Y95 Y96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:6da1, PDBe:6da1, PDBj:6da1
PDBsum6da1
PubMed30597162
UniProtP27577|ETS1_MOUSE Protein C-ets-1 (Gene Name=Ets1)

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