Structure of PDB 6d8p Chain B Binding Site BS01

Receptor Information
>6d8p Chain B (length=752) Species: 349102 (Cereibacter sphaeroides ATCC 17025) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQLVSNGFEVNLPDQVEVIVRDLPDPSKVKEERTRLMGYWFVHWFDGKLF
HLRIKAGGPNVDGEHRAIRTAEHPWLLRARLDDALEEALPKYAAVKKRPF
TFLAQKDELIDAAATAAGLSHRLLNSFKVIPRFALSPKIYEPVDGTTRVG
VFVTIGMRYDIEASLRDLLEAGIDLRGMYVVRRKRQRGLLGRVSDDMVQL
FEETDLASVNVNDAKLEGSKENFTRCLSALLGHNYKKLLNALDDQEAGYR
TGPRFDDAVRRMGEFLAKKPIRLADNINAQVGDRIVFSNEGQARNVRLAP
KVEYVFDRTGAKSAEYAWRGLSQFGPFDRPSFANRSPRILVVYPSSTQGK
VENFLSAFRDGMGSNYSGFSKGFVDLMGLTKVEFVMCPVEVSSADRNGAH
TKYNSAIEDKLAGAGEVHAGIVVLFEDHARLPDDRNPYIHTKSLLLTLGV
PTQQVRMPTVLLEPKSLQYTLQNFSIATYAKLNGTPWTVNHDKAINDELV
VGMGLAELSGSRTEKRQRFVGITTVFAGDGSYLLGNVSKECEYEGYSDAI
RESMTGILRELKKRNNWRPGDTVRVVFHAHRPLKRVDVASIVFECTREIG
SDQNIQMAFVTVSHDHPFVLIDRSERGLEAYKGSTARKGVFAPPRGAISR
VGRLTRLLAVNSPQLIKRANTPLPTPLLVSLHPDSTFKDVDYLAEQALKF
TSLSWRSTLPAATPVTIFYSERIAELLGRLKSIPNWSSANLNIKLKWSRW
FL
Ligand information
Receptor-Ligand Complex Structure
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PDB6d8p Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
P43 P45 W63 D65 R151 G175 M176 R177 Y178 G210 L211 E242 G243 K245 R275 A454 Y463 K467 Q478 Q479 V480 R481 T484 T495 N498 K506 R537 R543 K609 R610 K692 R731 S732 A737 F743 R754 L777
Binding residue
(residue number reindexed from 1)
P24 P26 W44 D46 R132 G156 M157 R158 Y159 G188 L189 E217 G218 K220 R250 A429 Y438 K442 Q453 Q454 V455 R456 T459 T470 N473 K481 R512 R518 K584 R585 K667 R706 S707 A712 F718 R729 L752
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0044355 clearance of foreign intracellular DNA

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Molecular Function

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Biological Process
External links
PDB RCSB:6d8p, PDBe:6d8p, PDBj:6d8p
PDBsum6d8p
PubMed29996105
UniProtA4WYU7|AGO_CERS5 Protein argonaute (Gene Name=ago)

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