Structure of PDB 6d50 Chain B Binding Site BS01

Receptor Information
>6d50 Chain B (length=840) Species: 1339349 (Bacteroides uniformis str. 3978 T3 ii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRQTQTINDSWKFLKGECTAAADSAFDDSKWTSIHLPHTWNTDAYTEKDY
YRGTGWYRRQLTLPQGWKEKQIILRLDAAGKSATIYINGKNVGEHAGGYT
ACSFNITPFLSFDTPNTLAVCVDNARQDIAPISGDFTFFGGIYRDVWLTA
VPNQHFNLTNHGSDGLFISTPQVSEEQATLSIRGEVKNDAPEKATLELTH
TIYRPDGTLLQTLKKNIQLKAGETYAFSNEATPVLKPELWTPETPRLYRV
ETTLRNRKTKTLLDQSNHYTAFRWFRFDGDEGFFLNGKPYKLRGICRHQD
QKPIGPALTDEMHRRDFLLMKEMGANFIRISHYPQDDALLEMCDKLGMLA
WEEIPIIDIVPNTPGYGDNCERNLREMIRQHYNHPSIITWGYMNEILLVT
QRKYKTEAELKPVLERTLALANRLERVLKEEDSTRISTMAFHGSNSYNET
GLSKITDIVGWNLYQGWYGGDLTGFEKFLAQQHQNHPTHPMIVSEYGAGS
DKRLHSLHPRAFDFSIEYQQKYLEHYLPVLEDTPYICGGTHWNFIDFSSA
LRDESMPRINNKGLVYADRTPKDVYHYYQAAWRKDIPVLHIASRDWTDRA
GVQQGNAPVYLPVKIYTNLSEVELFIDGISLGKQKTENYTATFEVPFSNR
NPFLFAQGNYQGKTVQDGLRINFTPIPACLDANNLKGLELAVNVGSQCFF
TSDESQLTWLPDQPYAAGSWGYIGGKEGTAQTEIQNTADGPLFQTLRNEI
EGYRFDAPQGVYEIELLFTDIFRRNRESTFGISINGEVVEESLSPCKESG
YFRALRKKYYITNDKEYIDIRFHSTSGTCFLNGIKLRNIY
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6d50 Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6d50 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D176 D341 D367
Binding residue
(residue number reindexed from 1)		D145 D310 D336
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6d50, PDBe:6d50, PDBj:6d50
PDBsum6d50
PubMed30301767
UniProtA0A078SUX9

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