Structure of PDB 6d4g Chain B Binding Site BS01

Receptor Information
>6d4g Chain B (length=187) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVGLSGTEKEKGQCGIGKSCLCNRFVRHTSVLSTSDFGGRVVNNDHFLYW
VEQTEFIDDQTFQPHRSPYIKRAAATKLASAEKLMYFCTDQLQMPDGKLL
VDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVIVLTKCDEGV
ERYIRDAHTFALSKKVETSARSNVNVDLAFSTLVQLI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6d4g Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6d4g The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
S36 E95
Binding residue
(residue number reindexed from 1)
S19 E52
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6d4g, PDBe:6d4g, PDBj:6d4g
PDBsum6d4g
PubMed30174148
UniProtP81128|RHG35_RAT Rho GTPase-activating protein 35 (Gene Name=Arhgap35)

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