Structure of PDB 6crp Chain B Binding Site BS01

Receptor Information
>6crp Chain B (length=247) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVPTYLLPGSGQFLTTDDHSSAPALPCFNPTPEMHIPGQVRNMLEVVQVE
SMMEINNTESAVGMERLKVDISALTDVDQLLFNIPLDIQLDGPLRNTLVG
NISRYYTHWSGSLEMTFMFCGSFMAAGKLILCYTPPGGSCPTTRETAMLG
THIVWDFGLQSSVTLIIPWISGSHYRMFNNDAKSTNANVGYVTCFMQTNL
IVPSESSDTCSLIGFIAAKDDFSLRLMRDSPDIGQLDHLHAAEAAYQ
Ligand information
>6crp Chain D (length=18) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NQINFYKDSYAASASKQD
Receptor-Ligand Complex Structure
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PDB6crp Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		D18 S20 S21 A22 P23 L25 C27
Binding residue
(residue number reindexed from 1)		D18 S20 S21 A22 P23 L25 C27
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6crp, PDBe:6crp, PDBj:6crp
PDBsum6crp
PubMed30530701
UniProtA0A097BW12

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