Structure of PDB 6cnl Chain B Binding Site BS01

Receptor Information
>6cnl Chain B (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KAKATRHIFLIRASQYHTLTPLGREQAELTGLRLASLGLKFNKIVHSSMT
RAIETTDIISRHLPGVCKVSTDLLREGAPIEPDPPVSHWKPEAVQYYEDG
ARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLR
LSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cnl Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
D184 P185 E247 R251
Binding residue
(residue number reindexed from 1)
D83 P84 E146 R150
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
External links
PDB RCSB:6cnl, PDBe:6cnl, PDBj:6cnl
PDBsum6cnl
PubMed30705304
UniProtQ96HS1|PGAM5_HUMAN Serine/threonine-protein phosphatase PGAM5, mitochondrial (Gene Name=PGAM5)

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