Structure of PDB 6cl1 Chain B Binding Site BS01
Receptor Information
>6cl1 Chain B (length=91) Species:
9606
(Homo sapiens) [
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KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFS
Ligand information
>6cl1 Chain E (length=3) Species:
32630
(synthetic construct) [
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PFD
Receptor-Ligand Complex Structure
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PDB
6cl1
Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
Resolution
2.651 Å
Binding residue
(original residue number in PDB)
Y230 S231 W232 R233
Binding residue
(residue number reindexed from 1)
Y19 S20 W21 R22
Enzymatic activity
Enzyme Commision number
3.4.22.60
: caspase-7.
Gene Ontology
Molecular Function
GO:0004197
cysteine-type endopeptidase activity
GO:0008234
cysteine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:6cl1
,
PDBe:6cl1
,
PDBj:6cl1
PDBsum
6cl1
PubMed
31334631
UniProt
P55210
|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)
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