Structure of PDB 6ckz Chain B Binding Site BS01

Receptor Information
>6ckz Chain B (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHLE
Ligand information
Receptor-Ligand Complex Structure
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PDB6ckz Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 N208 S209 S249 F256
Binding residue
(residue number reindexed from 1)		Y20 S21 W22 R23 N24 S25 S65 F72
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6ckz, PDBe:6ckz, PDBj:6ckz
PDBsum6ckz
PubMed31334631
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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