Structure of PDB 6c4u Chain B Binding Site BS01
Receptor Information
>6c4u Chain B (length=128) Species:
4932
(Saccharomyces cerevisiae) [
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GENIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHL
GNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGD
EITVRTDPTGTILSLVIFINDKFKQSLE
Ligand information
>6c4u Chain H (length=8) Species:
9606
(Homo sapiens) [
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LLPTPPLS
Receptor-Ligand Complex Structure
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PDB
6c4u
Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R70 L82 P83 S85 N86 T106 N107 R133
Binding residue
(residue number reindexed from 1)
R42 L54 P55 S57 N58 T78 N79 R105
Enzymatic activity
Enzyme Commision number
2.7.12.1
: dual-specificity kinase.
External links
PDB
RCSB:6c4u
,
PDBe:6c4u
,
PDBj:6c4u
PDBsum
6c4u
PubMed
29763736
UniProt
P22216
|RAD53_YEAST Serine/threonine-protein kinase RAD53 (Gene Name=RAD53)
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