Structure of PDB 6c1v Chain B Binding Site BS01

Receptor Information
>6c1v Chain B (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARY
LGNTVDLSSFDFRTGKMM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6c1v Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R166 S168 G169 L170 S171
Binding residue
(residue number reindexed from 1)		R20 S22 G23 L24 S25
Binding affinityPDBbind-CN: Kd=13uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1v, PDBe:6c1v, PDBj:6c1v
PDBsum6c1v
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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