Structure of PDB 6c1q Chain B Binding Site BS01

Receptor Information
>6c1q Chain B (length=374) Species: 562,9606 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDASPEMKDFRHGF
DILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYTLRVPDILAL
VIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPI
LFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKP
IWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVD
YSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRSTKTLKVVV
AVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCI
NPIIYVVAGQGFQSLPSLLRNVLT
Ligand information
Receptor-Ligand Complex Structure
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PDB6c1q Orthosteric and allosteric action of the C5a receptor antagonists.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		L178 P199 R261 R264 C274 G275 V276 S279 Y344 D368 V372
Binding residue
(residue number reindexed from 1)		L151 P172 R234 R237 C247 G248 V249 S252 Y313 D337 V341
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006935 chemotaxis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c1q, PDBe:6c1q, PDBj:6c1q
PDBsum6c1q
PubMed29867214
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P21730|C5AR1_HUMAN C5a anaphylatoxin chemotactic receptor 1 (Gene Name=C5AR1)

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