Structure of PDB 6bij Chain B Binding Site BS01
Receptor Information
>6bij Chain B (length=189) Species:
9606
(Homo sapiens) [
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DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTV
YPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA
Ligand information
>6bij Chain C (length=13) Species:
9606
(Homo sapiens) [
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GGYtAtPAKAAAT
Receptor-Ligand Complex Structure
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PDB
6bij
The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
H13 F26 Y30 D57 Y60 W61 L67 K71 T77 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)
H12 F25 Y29 D56 Y59 W60 L66 K70 T76 Y77 H80 N81 V84
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:6bij
,
PDBe:6bij
,
PDBj:6bij
PDBsum
6bij
PubMed
29317506
UniProt
P01911
|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)
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