Structure of PDB 6bha Chain B Binding Site BS01
Receptor Information
>6bha Chain B (length=100) Species:
9606
(Homo sapiens) [
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DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYAD
KLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHH
Ligand information
>6bha Chain C (length=4) Species:
9606
(Homo sapiens) [
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DEVD
Receptor-Ligand Complex Structure
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PDB
6bha
Modifications to a common phosphorylation network provide individualized control in caspases.
Resolution
1.603 Å
Binding residue
(original residue number in PDB)
Y204 S205 W206 R207 N208 S209 S249
Binding residue
(residue number reindexed from 1)
Y26 S27 W28 R29 N30 S31 S71
Enzymatic activity
Enzyme Commision number
3.4.22.56
: caspase-3.
Gene Ontology
Molecular Function
GO:0004197
cysteine-type endopeptidase activity
GO:0008234
cysteine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:6bha
,
PDBe:6bha
,
PDBj:6bha
PDBsum
6bha
PubMed
29414778
UniProt
P42574
|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)
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