Structure of PDB 6bfj Chain B Binding Site BS01

Receptor Information
>6bfj Chain B (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFM
HILTRVNRKVADEFEDFSFDATFHAKKQIPCIVSMLTKELYFYHH
Ligand information
Receptor-Ligand Complex Structure
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PDB6bfj Modifications to a common phosphorylation network provide individualized control in caspases.
Resolution1.543 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 N208 S209 D249
Binding residue
(residue number reindexed from 1)		Y21 S22 W23 R24 N25 S26 D66
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bfj, PDBe:6bfj, PDBj:6bfj
PDBsum6bfj
PubMed29414778
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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