Structure of PDB 6bdv Chain B Binding Site BS01
Receptor Information
>6bdv Chain B (length=93) Species:
9606
(Homo sapiens) [
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HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
Ligand information
>6bdv Chain C (length=4) Species:
32630
(synthetic construct) [
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DEVD
Receptor-Ligand Complex Structure
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PDB
6bdv
Modifications to a common phosphorylation network provide individualized control in caspases.
Resolution
1.938 Å
Binding residue
(original residue number in PDB)
Y204 S205 W206 R207 N208 S209
Binding residue
(residue number reindexed from 1)
Y20 S21 W22 R23 N24 S25
Enzymatic activity
Enzyme Commision number
3.4.22.56
: caspase-3.
Gene Ontology
Molecular Function
GO:0004197
cysteine-type endopeptidase activity
GO:0008234
cysteine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:6bdv
,
PDBe:6bdv
,
PDBj:6bdv
PDBsum
6bdv
PubMed
29414778
UniProt
P42574
|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)
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