Structure of PDB 6b45 Chain B Binding Site BS01

Receptor Information
>6b45 Chain B (length=305) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTDPEALLLLPRLSIQNANAISSPLTWGFPSPGAFTGFVHALQRRVGISL
DIELDGVGIVCHRFEAQISQPAGKRTKVFNLTRNPLNRDGSTAAIVEEGR
AHLEVSLLLGVHGDGLDDHPAQEIARQVQEQAGAMRLAGGSILPWCNERF
PAPNAELLMLGGSDEQRRKNQRRLTRRLLPGFALVSREALLQQHLETLRT
TLPEATTLDALLDLCRINFEPWQVRDKPGWLVPIPAGYNALSPLYLPGEV
RNARDRETPLRFVENLFGLGEWLSPHRVAALSDLLWYHHAEPDKGLYRWS
TPRFV
Ligand information
>6b45 Chain M (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guguaggcag
..................................................
..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6b45 Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		N21 P26 A36 G39 F40 R46 R85 N86 P87 M137 R138 L139 G141 R271 N282
Binding residue
(residue number reindexed from 1)		N19 P24 A34 G37 F38 R44 R83 N84 P85 M135 R136 L137 G139 R254 N265
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6b45, PDBe:6b45, PDBj:6b45
PDBsum6b45
PubMed28985564
UniProtQ02MM0|CSY2_PSEAB CRISPR-associated protein Csy2 (Gene Name=csy2)

[Back to BioLiP]