Structure of PDB 6ay7 Chain B Binding Site BS01

Receptor Information
>6ay7 Chain B (length=39) Species: 6858 (Androctonus australis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSVRIPVSCRHSGQCLRPCRDAGMRFGRCMNGRCDCTPR
Ligand information
Ligand IDTFA
InChIInChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChIKeyDTQVDTLACAAQTR-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01FC(F)(F)C(=O)O
CACTVS 3.370OC(=O)C(F)(F)F
OpenEye OEToolkits 1.7.0C(=O)(C(F)(F)F)O
FormulaC2 H F3 O2
Nametrifluoroacetic acid
ChEMBLCHEMBL506259
DrugBank
ZINCZINC000003860798
PDB chain6ay7 Chain B Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ay7 Cartilage homing cysteine-dense-peptides
Resolution1.77 Å
Binding residue
(original residue number in PDB)		H9 G11
Binding residue
(residue number reindexed from 1)		H11 G13
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008200 ion channel inhibitor activity
GO:0015459 potassium channel regulator activity
GO:0090729 toxin activity
Biological Process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ay7, PDBe:6ay7, PDBj:6ay7
PDBsum6ay7
PubMed
UniProtP45696|KAX35_ANDAU Potassium channel toxin alpha-KTx 3.5 (Gene Name=KTX2)

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