Structure of PDB 6atz Chain B Binding Site BS01

Receptor Information

>6atz Chain B (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TRPRFLEYSTSECHFFNGTERVRFLERYFHNQEENVRFDSDVGEYRAVTE
LGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTVY
PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA

Ligand information

>6atz Chain E (length=12) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GGYRARPAKAAT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6atz Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Resolution	2.7 Å
Binding residue (original residue number in PDB)	P56 D57 Y60 W61 R71 T77 Y78 H81 N82 V85
Binding residue (residue number reindexed from 1)	P54 D55 Y58 W59 R69 T75 Y76 H79 N80 V83

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:6atz, PDBe:6atz, PDBj:6atz
PDBsum	6atz
PubMed	28801345
UniProt	A0A0A1I7H6

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